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Commit 83925711 authored by tjc's avatar tjc
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update

git-svn-id: svn+ssh://svn.internal.sanger.ac.uk/repos/svn/pathsoft/artemis/trunk@11153 ee4ac58c-ac51-4696-9907-e4b3aa274f04
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......@@ -17,6 +17,10 @@ using and setting up an Artemis and ACT connection with a Chado database.
<h3><a name="DATABASEMANAGER">Opening the Database Manager</a></h3>
<p>
The Artemis Database Manager is cached between sessions in the directory
'.artemis/cache' in the users home directory. There is an option under the File menu
to clear this cache.
<p>
To open the Artemis Database Manager panel (from which the browser is launched),
Artemis looks initially for the existence of the cvterm.name = 'top_level_seq' which
belongs to cv.name = 'genedb_misc'. If these exist it follows method A:
......@@ -101,32 +105,68 @@ Feature. The joined exons become an Artemis CDS feature (GFFStreamFeature), whic
the uniquenames of the original exons in the database.
<p>
<h3><a name="CONFIG">Option File Configuration</a></h3>
<p>
Artemis combines the exons stored in chado and describes it as an 'exon-model'
feature by default (defined by uk.ac.sanger.artemis.util.DatabaseDocument.EXONMODEL).
The chado_exon_model flag in the options file allows this to be changed.
<p>
When a gene model is created in Artemis it creates the transcript as a 'mRNA'
feature by default (defined by uk.ac.sanger.artemis.util.DatabaseDocument.TRANSCRIPT).
The chado_transcript flag in the options file allows this to be changed.
<p>
A list of available databases can be configured in the options file (chado_servers flag).
For each an alias is given followed by its location (host:port/database?user), each alias
is displayed in a drop down menu in the login box.
<h3><a name="CONFIG">Artemis Chado Configuration</a></h3>
This is an example extract from the Artemis options file for the chado related options:
<p>
Below is an example configuration option:
<pre>
<pre style="color: #0000FF;">
#
# CHADO DATABASE OPTIONS
#
# chado gene model features default types
chado_exon_model=CDS
#chado_transcript=transcript
# infer CDS and UTR features from gene model
chado_infer_CDS_UTR=no
# provide a list of available servers
chado_servers = \
test localhost:5432/test?userName \
genedb_ro db.genedb.org:5432/snapshot?genedb_ro
workshop localhost:10101/workshop?user \
GeneDB db.genedb.org:5432/snapshot?genedb_ro
# define how product qualifiers are stored (as a cv or as a featureprop)
product_cv=yes
product_cvname = genedb_products
# cv containing synonym names
synonym_cvname = genedb_synonym_type
# set default delete behaviour to make things obsolete, if
# this is not provided the default is to permanently delete
set_obsolete_on_delete=yes
# list of features to record residues for in the database
# - these are included when inserting or updating their featurelocs
sequence_update_features = polypeptide mRNA rRNA tRNA snRNA snoRNA
</pre>
<p>
Artemis combines the exons stored in chado and describes it as a 'CDS'
feature by default. The <b>chado_exon_model</b> flag in the options file
allows this to be changed.
<p>
When a gene model is created in Artemis it creates the transcript as a 'mRNA'
feature by default. The <b>chado_transcript</b> flag in the options file allows this
to be changed.
<p>
For Artemis the default gene model representation is described in the <a href="overview.shtml#GENE">
overview</a>. In this representation the UTRs are explicitly created in the database.
However the gmod loader (gmod_bulk_load_gff3.pl) does not create the UTRs and they can
be inferred from the exon and protein features. If the gmod loader is used then Artemis
can infer the CDS and UTR features by setting <b>chado_infer_CDS_UTR=yes</b> in the
options file.
<p>
A list of available databases can be configured in the options file with the <b>chado_servers</b> flag.
For each database an alias is given followed by its location (host:port/database?user), each alias
is displayed in a drop down menu in the login box.
<p>
If product qualifiers are stored as an ontology (in cvterm) then set <b>product_cv=yes</b>
and set <b>product_cvname</b> is set to the name of the controlled vocabulary (cv) used in chado.
<p>
When features are deleted in Artemis the default behaviour can be set to make these
features obsolete rather than permanently delete them from the database.
<a name="GENEBUILDER"></a><h3>Opening the Standalone Gene Builder</h3>
<p>
The Gene Builder can be launched on its own without opening up Artemis. The following
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......@@ -25,7 +25,9 @@
The address of the database (hostname, port and name) can be conveniently
included as follows:
<br><pre>-Dchado="hostname:port/test?username"</pre>
So that these details are already completed in the popup login pane.
these details are then the default database address in the popup login window. A
list of available databases can be provided in the Artemis <a href="admin.shtml#CONFIG">options file</a>
these are presented in a drop down list in the login window.
<br><br>
<img src="login.gif" align="middle" alt="login"/>
<br>
......@@ -53,7 +55,9 @@ For a read only connection -Dread_only is specified on the command line:
On a successful login a database and file manager window will open up.
The database manager will display "Database Loading...". The organisms
in the database with residues are shown in a expandable tree. Double
clicking on the sequence names opens them up in Artemis.
clicking on the sequence names opens them up in Artemis. Alternatively
a gene name or chromosome name came be typed into the text field at the
top and the Open button used to launch Artemis.
<br><br>
<img src="databasemanager.gif"/>
<p>
......@@ -103,6 +107,10 @@ For a read only connection -Dread_only is specified on the command line:
automatically generated by the gene builder from an ID provided by the
user. <i>N.B.</i> in our data model UTRs are represented as distinct from
exons.
<p>
For the scenario where both the CDS and UTRs are not stored and their positions can be
inferred from the exon and polypeptide features set <i>chado_infer_CDS_UTR=yes</i> in the
Artemis <a href="admin.shtml#CONFIG">options file</a>.
<a NAME="GENEBUILDING"></a><h3>Gene Building</h3>
A gene can be created in Artemis (or ACT) by highlighting a base range and selecting
from the '<i>Create</i>' menu the '<i>Gene Model From Base Range</i>' option.
......@@ -302,7 +310,7 @@ For a read only connection -Dread_only is specified on the command line:
These mappings are stored in the 'etc/key_mapping' and 'etc/qualifier_mapping'
files.
<p>
A script (etc/write_db_entry) is also provided as a means of writing out multiple
A script (etc/writedb_entry) is also provided as a means of writing out multiple
sequences from the database. The script takes the following options:
<pre>
-h show help
......@@ -310,5 +318,6 @@ For a read only connection -Dread_only is specified on the command line:
-i [y|n] ignore obsolete features, default is y
-s space separated list of sequences to read and write out
-o [EMBL|GFF] output format, default is EMBL
-a [y|n] for EMBL submission format change to n, default is y
</pre>
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